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PE-NORDIC Study

Reperfusion Treatment in Acute Pulmonary Embolism: A Multicenter Observational Study in the Nordic Countries

Study Overview

PE-NORDIC is a prospective observational multicenter study comparing outcomes of different treatment strategies for acute pulmonary embolism.

Study Design

Prospective multicenter observational cohort study in Sweden and Denmark.

Eligibility

Adult patients with acute pulmonary embolism treated with CDI or ST.

Timeline

Three-year inclusion period from Q2 2025 to Q2 2028.

Purpose

PE-NORDIC is a comprehensive multicenter study designed to advance our understanding of severe pulmonary embolism and evaluate the effectiveness and safety of current treatment approaches.

Pulmonary embolism remains a significant health concern with high mortality rates in severe cases, requiring immediate intervention to restore blood flow. Currently, two main reperfusion strategies exist: systemic thrombolysis and catheter-directed interventions. Despite the increasing adoption of catheter-directed techniques in both high-risk and intermediate-risk patients, there is a notable lack of comparative evidence between catheter-directed treatment and standard of care. This study aims to address this critical knowledge gap and provide essential data to help guide clinical decision-making.

Participating Centers

The study is being conducted across multiple centers in Sweden and Denmark.

Sweden

  • Sahlgrenska University Hospital, Gothenburg
  • Uppsala University Hospital, Uppsala
  • Karolinska University Hospital, Stockholm
  • Södersjukhuset, Stockholm
  • Danderyd Hospital, Stockholm
  • Karolinska University Hospital Solna, Stockholm
  • Karolinska University Hospital Huddinge, Stockholm
  • Linköping University Hospital, Linköping
  • Sunderby Hospital, Luleå
  • Örebro University Hospital
  • Malmö/Lund University Hospital

Denmark

  • Aarhus University Hospital
  • Odense University Hospital
  • Rigshospitalet (Copenhagen)

Our goal

Vårt mål är att behandla 220 patienter

Behandlade patienter maj 2025

Contact Us

Have questions about the PE-NORDIC study?

Fundings

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Forskning och Utveckling (FoU) i VGR

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Stiftelsen Elsa och Gustav Lindhs fond

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Partners

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Sahlgrenska Universitetssjukhuset

Blå stråket 5

413 45 Göteborg, Sweden