Purpose

PE-NORDIC is a comprehensive multicenter study designed to advance our understanding of severe pulmonary embolism and evaluate the effectiveness and safety of current treatment approaches.

Pulmonary embolism remains a significant health concern with high mortality rates in severe cases, requiring immediate intervention to restore blood flow. Currently, two main reperfusion strategies exist: systemic thrombolysis and catheter-directed interventions. Despite the increasing adoption of catheter-directed techniques in both high-risk and intermediate-risk patients, there is a notable lack of comparative evidence between catheter-directed treatment and standard of care. This study aims to address this critical knowledge gap and provide essential data to help guide clinical decision-making.